Target Pituitary

Physician Psychiatric Medication Information Service

In response to continuing developments of new treatments for patients with pituitary disease, the Neuroendocrine and Pituitary Clinical Center offers an information service for physicians.

To contact us, physicians with questions may dial toll free: 1-888-429-6863 or email us at: pituitary.info@partners.org

All inquiries will be responded to within two weeks of receipt.

Karren K. Miler, M.D., Director, Neuroendocrine and Pituitary Tumor Clinical Center

NEPTCC Services

  • The Neuroendocrine and Pituitary Tumor Clinical Center offers:

    • Detailed outpatient evaluations of all disorders affecting the hypothalamus and pituitary gland
    • Complete basal and dynamic hormone testing
    • Coordination of endocrine evaluations, radiological studies, visual field testing, and surgical and radiation therapy consultations.
    • A diagnostic and therapeutic plan formulated for each patient and provided to the referring physician
    • A weekly multidisciplinary case conference at which complex cases are presented
    • The opportunity to participate in clinical research designed to enhance the care of patients with pituitary disorders
    • Workshops for patients and families


  • The Neuroendocrine and Pituitary Tumor Clinical Center works with referring physicians to provide the following:

    • Consultative evaluations of patients with pituitary disorders
    • Complete basal and dynamic hormone testing
    • Coordination of endocrine evaluations, radiological studies, visual field testing, and surgical and radiation therapy consultations.
    • A diagnostic and therapeutic plan formulated for each patient and provided to the referring physician
    • A weekly multidisciplinary case conference at which complex cases are presented
    • A research program designed to enhance the care of patients with rare pituitary disorders
    • Medical education specifically in the area of pituitary disorders: educational presentations by our faculty, a Neuroendocrine Bulletin and postgraduate educational opportunities

    In response to continuing developments of new treatments for patients with pituitary disease, the Neuroendocrine and Pituitary Tumor Clinical Center offers an Information Service for Physicians. The purpose is to support physicians in the care of their patients by providing access to the most recent information and research regarding pituitary disease and its treatment.

    Physician Pituitary Information Service - Physicians with questions may contact:



  • Clinical and Basic Research Studies -- We are actively recruiting participants for several research studies described on this site and we hope that you will consider participating. These studies are designed to advance our understanding of pituitary disorders and improve treatment for pituitary patients.

    • Patients may qualify for research studies in the Neuroendocrine and Pituitary Tumor Clinical Center. We are currently accepting patients for screening to determine study eligibility.
    • Depending on the study, subjects may receive free testing, medication and/or stipends.


  • Patient Education -- There is a wealth of information designed for patients about pituitary disease on this website, on the Pituitary Society website and in the Neuroendocrine and Pituitary Tumor Clinical Center Bulletins.

    Physician Education --

    • The MGH/Harvard Medical School postgraduate course Clinical Endocrinology is held annually in Boston and includes a full day on pituitary topics.
    • The Neuroendocrine and Pituitary Tumor Clinical Center Bulletin provides updates on pituitary disease topics.


  • Meuroendocrine Center Bulletin

  • Patients & Families with questions about referrals, consultations, 2nd opinions or appointments may contact:

    Special Instructions (If available, please bring):

    • Copies of your medical records/discharge summary/physician notes.
    • A copy of your MRI or CT on a CD.
    • A copy of your lab reports.
    • Bring any medications you are taking with you to your appointment.
    • Please make sure your MGB registration is accurate and up-to-date.

    Our clinic assistants will help you update your hospital registration and insurance information.





Our Experts - At Your Service

Target Pituitary

For Physicians and Scientists

Pituitary disease experts Beverly MK Biller, M.D. and Karen K. Miller M.D. support physicians in the care of their patients by providing access to the most recent information and research regarding pituitary disease and treatment

To contact us, physicians with questions may dial toll free: 1-888-429-6863 or email us at: pituitary.info@partners.org

The most common questions related to psychiatric medications and the neuroendocrine system relate to hyperprolactinemia. Topics frequently addressed include the following:

  • physiology of hyperprolactinemia
  • clinical issues in hyperprolactinemia
    • amenorrhea
    • galactorrhea
    • decreased libido
    • erectile dysfunction
    • male hypogonadism
    • osteoporosis
  • diagnosis of neuroleptic-induced hyperprolactinemia
  • diagnosis of prolactinoma
  • role of head MRI scans
  • management options in hyperprolactinemia-induced hypogonadism
  • risks of hyperprolactinemia versus a change in psychiatric medications


Special Expertice

Target Pituitary

For Physicians and Scientists

In addition to expertise related to neuroleptic-induced hyperprolactinemia, other areas in which the Neuroendocrine and Pituitary Tumor Clinical Center provides special multidisciplinary expertise include:

  • Pituitary tumors - Prolactinomas; Cushing’s disease; acromegaly; clinically non-functioning adenomas and TSH-secreting adenomas
  • Cushing’s Syndrome - Pituitary Cushing’s; ectopic Cushing’s; adrenal Cushing’s; Iatrogenic Cushing’s
  • Hypopituitarism - Central hypoadrenalism; hypothyroidism; hypogonadism; growth hormone deficiency
  • Posterior pituitary dysfunction - Diabetes insipidus; syndrome of inappropriate antidiuretic hormone secretion
  • Prolactin disorders - Amenorrhea-galactorrhea syndromes; drug induced hyperprolactinemia; infertility; male hypogonadism
  • Sellar and suprasellar lesions - Craniopharyngiomas; cystic tumors; sellar-region meningiomas; inflammatory disorders; metastatic disease involving the pituitary or hypothalamus and other sellar masses