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What is a Non-Functioning Pituitary Tumor? The majority of patients with pituitary adenomas present with signs and symptoms reflecting excess hormone production. Approximately 25-30% of patients with pituitary tumors do not have classical hypersecretory syndromes such as hyperprolactinemia, acromegaly or Cushing's disease and present as the case described above. These tumors are referred to as clinically nonfunctioning adenomas (see Figure 1) Patients often present with signs of mass effects, including headaches and symptoms of pituitary insufficiency In addition, compression of the optic chiasm frequently results in temporal field deficits Recent progress in our ability to characterize and diagnose these tumors will be discussed here.
Neuroendocrine Bulletin Archive
[Neuroendocrine Clinical Home]
Profiles of the Endocrine Clinic: A Decade of the Massachusetts General Hospital Neuroendocrine Clinical Center.

[Neuroendocrine Clinical Home]
Anne Klibanski, M.D., 
Director, Neuroendocrine Clinical Center

Patients & Families with questions about referrals, consultations or appointments may contact:

Voice:  617.726.7948
Fax:  617.726.1241

(Maps of MGH)

Outpatient clinic visits and inpatient consultations can be arranged by calling the Neuroendocrine Clinical Center office. Physicians with questions may contact Dr. Grinspoon at 617.726.7948


Physicians with questions may contact:

Dr Biller or Dr Klibanski at
617.726.3965 or 1.888.429.6863

[Neuroendocrine Clinical Home] Profiles of the
Neuroendocrine Clinic
The Neuroendocrine Clinical Center was founded in 1985, in order to provide a multidisciplinary approach to patients with pituitary and hypothalamic disorders.
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    Disclaimer About Medical Information: The information and reference materials contained herein is intended solely for the information of the reader. It should not be used for treatment purposes, but rather for discussion with the patient's own physician. All visitors to this and associated sites from the Neurosurgical Service at MGH agree to read and abide by the the complete terms of legal agreement found at the Neurosurgery "disclaimer & legal agreements."
    Voice:  617.726.7948
    Fax:  617.726.1241

    Physicians' Pituitary Information Service - Physicians with questions may contact Dr Biller or DR Klibanski at 617.726.3965 or 1.888.429.6863 or via e-mail at


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