Conditions & Treatments

Committed to Patient Care

Target Pituitary

For over two decades, the Massachusetts General Hospital Neuroendocrine and Pituitary Clinical Center has provided a multidisciplinary approach to patients with pituitary and hypothalamic disorders.

Although the Neuroendocrine Unit is rooted in scientific advancement, our team of more than 20 full-time clinicians is deeply committed to day-to-day patient care. Our phyiscians evaluate and manage patients through the Neuroendocrine and Pituitary Clinical Center, a multidisciplinary care center made up of expert endocrinologists, neurosurgeons, neurologists, radiation oncologists, and nurses. Our specialists diagnose and manage the full range of neuroendocrine conditions

Team of Experienced Specialists

Target Pituitary

The Neuroendocrine and Pituitary Clinical Center at Massachsuetts General Hospital provides diagnostic services and medical treatments for pituitary disorders including prolactinomas and acromegaly. Our endocrinologists are experienced in the chronic administration of replacement hormones and in the use of drugs which threat hormone excess syndromes, including investigational drugs for the treatment of prolactin and growth hormone disorders.

Our specialists diagnose and manage the full range of neuroendocrine conditions, including:

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Latest Research & Clinical Trials

Target Pituitary

Physicians at the Neuroendocrine and Pituitary Tumor Clinical Center conduct research and clinical trials, allowing us to bring our patients promising new treatments as quickly as possible.

Our goal is to better understand pituitary disease and develop novel treatments that will help improve clinical care for patients with neuroendocrine disorders and neuroendocrine malignancies. Research at the Neuroendocrine and Pituitary Clinical Center at Mass General is divided into four major research areas including:

  • Pathogenesis and regulation of human pituitary adenomas
  • Pathophysiology of neuroendocrine disorders
  • Relationship between nutritional disorders and neuroendocrine factors
  • Development of novel therapies for patients with pituitary and hypothalamic disorders

... read more ...


NECC Services

  • The Neuroendocrine and Pituitary Tumor Clinical Center offers:

    • Detailed outpatient evaluations of all disorders affecting the hypothalamus and pituitary gland
    • Complete basal and dynamic hormone testing
    • Coordination of endocrine evaluations, radiological studies, visual field testing, and surgical and radiation therapy consultations.
    • A diagnostic and therapeutic plan formulated for each patient and provided to the referring physician
    • A weekly multidisciplinary case conference at which complex cases are presented
    • The opportunity to participate in clinical research designed to enhance the care of patients with pitutary disorders
    • Workshops for patients and families


  • The Neuroendocrine and Pituitary Tumor Clinical Center works with referring physicians to provide the following:

    • Consultative evaluations of patients with pituitary disorders
    • Complete basal and dynamic hormone testing
    • Coordination of endocrine evaluations, radiological studies, visual field testing, and surgical and radiation therapy consultations.
    • A diagnostic and therapeutic plan formulated for each patient and provided to the referring physician
    • A weekly multidisciplinary case conference at which complex cases are presented
    • A research program designed to enhance the care of patients with rare pitutary disorders
    • Medical education specifically in the area of pituitary disorders: educational presentations by our faculty, a Neuroendocrine Bulletin and postgraduate educational opportunities

    In response to continuing developments of new treatments for patients with pituitary disease, the Neuroendocrine and Pituitary Tumor Clinical Center offers an Information Service for Physicians. The purpose is to support physicians in the care of their patients by providing access to the most recent information and research regarding pituitary disease and its treatment.

    Physician Pituitary Information Service - Physicians with questions may contact:



  • Clinical and Basic Research Studies -- We are actively recruiting participants for several research studies described on this site and we hope that you will consider participating. These studies are designed to advance our understanding of pituitary disorders and improve treatment for pituitary patients.

    • Patients may qualify for research studies in the Neuroendocrine and Pituitary Tumor Clinical Center. We are currently accepting patients for screening to determine study eligibility.
    • Depending on the study, subjects may receive free testing, medication and/or stipends.


  • Patient Education -- There is a wealth of information designed for patients about pituitary disease on this website, on the Pituitary Society website and in the Neuroendocrine and Pituitary Tumor Clinical Center Bulletins.

    Physician Education --

    • The MGH/Harvard Medical School postgraduate course Clinical Endocrinology is held annually in Boston and includes a full day on pituitary topics. Save the date for the 2016 course (March 20-24, 2016).
    • The Neuroendocrine and Pituitary Tumor Clinical Center Bulletin provides updates on pituitary disease topics.
    • Workshops on management of pituitary disease can be arranged for physician groups (of 12 or more).

    For more details, please contact:

    • Shelly Riley
      MGH Office for Visitor Education Programs
      55 Fruit Street CAM326-510N
      Boston, MA 02114
      (617) 726-8363
      mghvep@partners.org


  • Neuroendocrine and Pituitary Tumor Clinical Center Bulletin -- Volume 20, Issue 1, Spring 2013

    • Sellar Masses Are Not Always Pituitary Adenomas – What Are the Diagnostic Possibilities? by Brooke Swearingen, MD
    • Cardiovascular Effects of Acromegaly by Alexander Faje, MD
    • Research Studies Available
    • Physicians’ Pituitary Information Service (PPIS) pituitary.info@partners.org


  • Patients & Families with questions about referrals, consultations, 2nd opinions or appointments may contact:

    Special Instructions (If available, please bring):

    • Copies of your medical records/discharge summary/physician notes.
    • A copy of your MRI or CT on a CD.
    • A copy of your lab reports.
    • Bring any medications you are taking with you to your appointment.
    • Please make sure your MGH registration is accurate and up-to-date.

    Our clinic assistants will help you update your hospital registration and insurance information.

    • Physicians who would like to refer patients:
      • Referrals for neuroendocrine evaluation, e-mail Dr. Nachtigall or call 617.726.7948.
      • Referrals for surgical evaluation, email Dr. Swearingen or call 617-726-3910.




Disclaimer About Medical Information: The information and reference materials contained herein is intended solely for the information of the reader. It should not be used for treatment purposes, but rather for discussion with the patient's own physician. All visitors to this and associated sites from the Neurosurgical Service at MGH agree to read and abide by the the complete terms of legal agreement found at the Neurosurgery "disclaimer & legal agreements."

Physicians' Pituitary Information Service - Physicians with questions may contact Dr Biller or Dr Klibanski at 617.726.3965 or 1.888.429.6863 or via e-mail at - pituitary.info@partners.org :: Research Studies

The Neuroendocrine and Pituitary Tumor Clinical Center
Massachusetts General Hospital
Zero Emerson Place, Suite 112, Boston, Massachusetts 02114
Voice: 617.726.7948 & Fax: 617.726.1241
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