| SUBJECTS | STUDIES | CONTACT 617-726-3870 |
| Newly
diagnosed acromegaly | · Evaluating
preoperative medical treatments | Karen
Pulaski-Liebert, R.N. Dr.
Beverly M.K. Biller |
| Cushing’s
Syndrome | · Evaluating
a potential new medical therapy | Karen
Pulaski-Liebert, R.N. Dr.
Beverly M.K. Biller |
| Patients
with active acromegaly | · Body
composition and cardiovascular evaluation | Dr.
Anne Klibanski Dr.
Tamara Wexler |
| Patients
with history of cured acromegaly with or without hypopituitarism | ·
Body composition and cardiovascular
evaluation ·
GH replacement study in patients
with GH deficiency
| Dr.
Anne Klibanski Dr.
Tamara Wexler |
| Adolescent
girls with anorexia nervosa | ·
Evaluating bone density and
the effects of estrogen replacement ·
Newer therapeutic possibilities
| Dr.
Anne Klibanski Dr.
Madhu Misra |
| Healthy
adolescent girls and boys |
· To
determine extent of growth hormone suppression following an oral glucose load |
Dr.
Anne Klibanski Dr.
Madhu Misra |
| Healthy
and overweight adolescent girls, ages 12-18 | · Investigating
body weight in relation to GH and ghrelin secretion in adolescents
| Dr.
Anne Klibanski Dr.
Madhu Misra |
| Women
and adolescent girls with anorexia nervosa | ·
Investigating effects of
rhGH on bone metabolism | Dr.
Anne Klibanski Dr.
Madhu Misra |
| Women
with anorexia nervosa | ·
New therapies | Dr.
Karen K. Miller Dr.
Anne Klibanski |
| Women
and men, ages 18-45 | ·
Investigating
body weight and GH secretion · GH
treatment in abdominal obesity | Dr.
Andrea Utz Dr.
Karen K. Miller |
| Healthy
women, ages 18-45 | ·
Investigating the link between
cortisol regulation and bone density | Dr.
Elizabeth Lawson Dr.
Karen K Miller Dr.
Anne Klibanski |
| Women
with irregular menstrual periods (hypothalamic amenorrhea), ages 18-45 | ·
Investigating the link between
cortisol regulation and bone density | Dr.
Elizabeth Lawson Dr.
Karen K Miller Dr.
Anne Klibanski |
| Men
and Women with the Metabolic Syndrome (Obesity and Insulin resistance) | ·
Evaluating effects of TNF-alpha
neutralization, to reduce inflammation | Dr.
Steven Grinspoon Dr.
Stine Johnsen |
| HIV
positive men and women with fat redistribution | ·
Assessment of coronary artery
calcification ·
Lifestyle modification strategies,
including exercise and insulin sensitization
| Dr.
Steven Grinspoon Dr.
Janet Lo Katie
Fitch, ANP |
| HIV
positive men and women with fat redistribution | ·
Use of GHRH, a growth hormone
secretagogue, to increase endogenous GH levels, improve fat distribution and lipid
profile ·
Among patients with reduced
GH response to standard GH secretion testing, use of low dose GH as above
| Dr.
Steven Grinspoon Janet
Lo, M.D. Jim
Liebau, ANP |