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RESEARCH STUDIES AVAILABLE

Physicians at the Neuroendocrine Clinical Center at Massachusetts General Hospital are conducting several exciting research studies aimed at understanding and addressing medical issues related to pituitary disorders and learning more about the mechanisms of anorexia nervosa and applying novel treatments that will help improve future clinical treatments.

We are actively recruiting participants for several research studies described on this site and we hope that you will consider participating. We encourage you to investigate the educational material provided regarding pituitary disorders, and please do not hesitate to contact us if you would like further information.

Patients may qualify for research studies in the Neuroendocrine Clinical Center.  We are currently accepting the following categories of patients for screening to determine study eligibility.  Depending on the study, subjects may receive free testing, medication and/or stipends. [ see Neuroendocrine Links for more information ]
Clinical Research Studies (overview - this page)
Clinical Research Studies in Pituitary Disorders (new)
Clinical Research Studies in Anorexia Nervosa (new)

RESEARCH STUDIES AVAILABLE

SUBJECTS

STUDIES

CONTACT
 617-726-3870

Newly diagnosed acromegaly

· Evaluating preoperative medical treatments

Karen Pulaski-Liebert, R.N.

Dr. Beverly M.K. Biller

Cushing’s Syndrome

· Evaluating a potential new medical therapy

Karen Pulaski-Liebert, R.N.

Dr. Beverly M.K. Biller

Patients with active acromegaly

· Body composition and cardiovascular evaluation

Dr. Anne Klibanski

Dr. Tamara Wexler

Patients with history of cured acromegaly with or without hypopituitarism

· Body composition and cardiovascular evaluation

· GH replacement study in patients with GH deficiency

Dr. Anne Klibanski

Dr. Tamara Wexler

Adolescent girls with anorexia nervosa

· Evaluating bone density and the effects of estrogen replacement

· Newer therapeutic possibilities

Dr. Anne Klibanski

Dr. Madhu Misra

Healthy adolescent girls and boys

· To determine extent of growth hormone suppression following an oral glucose load

Dr. Anne Klibanski

Dr. Madhu Misra

Healthy and overweight adolescent girls, ages 12-18

· Investigating body weight in relation to GH and ghrelin secretion in adolescents

Dr. Anne Klibanski

Dr. Madhu Misra

Women and adolescent girls with anorexia nervosa

· Investigating effects of rhGH on bone metabolism

Dr. Anne Klibanski

Dr. Madhu Misra

Women with anorexia nervosa

· New therapies

Dr. Karen K. Miller

Dr. Anne Klibanski

Women and men, ages 18-45

· Investigating body weight and GH secretion

· GH treatment in abdominal obesity

Dr. Andrea Utz

Dr. Karen K. Miller

Healthy women, ages 18-45

· Investigating the link between cortisol regulation and bone density

Dr. Elizabeth Lawson

Dr. Karen K Miller

Dr. Anne Klibanski

Women with irregular menstrual periods (hypothalamic amenorrhea), ages 18-45

· Investigating the link between cortisol regulation and bone density

Dr. Elizabeth Lawson

Dr. Karen K Miller

Dr. Anne Klibanski

Men and Women with the Metabolic Syndrome (Obesity and Insulin resistance)

· Evaluating effects of TNF-alpha neutralization, to reduce inflammation

 

Dr. Steven Grinspoon

Dr. Stine Johnsen

HIV positive men and women with fat redistribution

· Assessment of coronary artery calcification

· Lifestyle modification strategies, including exercise and insulin sensitization

Dr. Steven Grinspoon

Dr. Janet Lo

Katie Fitch, ANP

HIV positive men and women with fat redistribution

· Use of GHRH, a growth hormone secretagogue, to increase endogenous GH levels, improve fat distribution and lipid profile

· Among patients with reduced GH response to standard GH secretion testing, use of low dose GH as above

Dr. Steven Grinspoon

Janet Lo, M.D.

Jim Liebau, ANP

 

[ Clinical Research Studies in Pituitary Disorders and Clinical Research Studies in Anorexia Nervosa ]

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MASSGENERAL
LEGAL ISSUES

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Disclaimer About Medical Information: The information and reference materials contained herein is intended solely for the information of the reader. It should not be used for treatment purposes, but rather for discussion with the patient's own physician. All visitors to this and associated sites from the Neurosurgical Service at MGH agree to read and abide by the the complete terms of legal agreement found at the Neurosurgery "disclaimer & legal agreement." See also: the MGH Disclaimer, the MGH Privacy Policy, and the MGH Interactive Program Disclaimer - Visitors must read the disclaimer - legal agreement. All Rights Reserved. Copyright © 2007 MGH Neuroendocrin Clinical Center - e-mail C.Owen
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MGH  Neurosurgical Service Home

Neuroendocrine
Clinical Center

Physicians' Pituitary Information Service - Physicians with questions may contact Dr Biller or DR Klibanski at 617.726.3965 or 1.888.429.6863 or via e-mail pituitary.info@partners.org
Voice:  617.726.7948
Fax:  617.726.1241

Clinical Research Studies
Clinical Research Studies in Pituitary Disorders
Clinical Research Studies in Anorexia Nervosa