Physicians at the Neuroendocrine Clinical Center at Massachusetts General Hospital are conducting several exciting research studies aimed at understanding and addressing medical issues related to pituitary disorders and learning more about the mechanisms of anorexia nervosa and applying novel treatments that will help improve future clinical treatments.

We are actively recruiting participants for several research studies described on this site and we hope that you will consider participating. We encourage you to investigate the educational material provided regarding pituitary disorders, and please do not hesitate to contact us if you would like further information.

Patients may qualify for research studies in the Neuroendocrine Clinical Center.  We are currently accepting the following categories of patients for screening to determine study eligibility.  Depending on the study, subjects may receive free testing, medication and/or stipends. [ see Neuroendocrine Links for more information ]

 

Clinical Research Studies (overview - this page) Clinical Research Studies in Pituitary Disorders Clinical Research Studies in Anorexia Nervosa SportsEndocrineResearch.com (new) aims to provide information about our research group at MGH and the ongoing studies we are conducting. It serves to inform both currently enrolled and prospective participants about our studies in an effort to further medical research and knowledge about common endocrine issues facing athletes today.

RESEARCH STUDIES AVAILABLE (see latest Neuroendocrin Bulletin)
Patients may qualify for research studies in the Neuroendocrine Clinical Center. We are currently accepting the following categories of patients for screening to determine study eligibility. Depending on the study, subjects may receive free testing, medication and/or stipends.

SUBJECTS	STUDIES	CONTACT 617-726-3870
Adults with GHD	Diagnostic testing for GHD	Karen Pulaski Liebert, RN Beverly M.K. Biller, MD
Adults with Cushing’s	Study investigating new medication to treat Cushing’s	Karen Pulaski Liebert, RN Beverly M.K. Biller, MD
Adolescent and young adult athletes	Investigating impact of hormonal alterations on menstrual function and bone density	Dr. Madhu Misra Dr. Anne Klibanski
Obese adolescent girls	Investigating impact of growth hormone on body fat distribution and metabolic function	Dr. Madhu Misra Dr. Anne Klibanski
Adolescent girls with anorexia nervosa	Investigating the impact of new therapies on bone density	Dr. Madhu Misra Dr. Anne Klibanski Dr. Karen K. Miller
Women with anorexia nervosa	New therapies	Dr. Karen K. Miller Dr. Anne Klibanski
Women ages 18-30 with a history of anorexia nervosa	Investigating hormones and brain circuitry involved in appetite	Dr. Elizabeth Lawson Dr. Anne Klibanski
Men ages 18-45	Investigating body weight and GH secretion GH treatment in abdominal obesity	Dr. Karen K. Miller
Girls and women with current anorexia nervosa or a history of anorexia nervosa, ages 10 and up	Investigating genetics of appetite-regulating and stress hormones	Dr. Elizabeth Lawson Dr. Karen K. Miller Dr. Anne Klibanski Dr. Madhu Misra
Obese men and women	Use of GHRH, a growth hormone secreta- gogue, to increase endogenous GH levels, improve fat distribution and lipid profile	Dr. Hideo Makimura Dr. Steven Grinspoon
Overweight children	Effects of exercise on mitochondrial function	Dr. Amy Fleischman Dr. Steven Grinspoon
HIV positive men and women	Assessment of coronary artery atherosclerosis with and without metabolic abnormalities\ Lifestyle modification strategies, including exercise and insulin sensitization Growth hormone and growth hormone releasing hormone Assessment of long-term GHRH Assessment of brown fat Assessment of menopausal transition Statin therapy for coronary plaque	Dr. Steven Grinspoon Dr. Janet Lo Katie Fitch, ANP Dr. Takara Stanley

[ Clinical Research Studies in Pituitary Disorders and Clinical Research Studies in Anorexia Nervosa ]